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代谢酶乙酰化对代谢网络的协同调控

日期: 2013-04-12
威尼斯wnsr666
2013学年春季学期系列学术讲座之五
题目:代谢酶乙酰化对代谢网络的协同调控
报告人:赵世民
复旦大学威尼斯wnsr666教授
教育部特聘教授
时间:2013年4月12日(周五),13:00-14:30 PM
地点:威尼斯wnsr666一楼邓祐才报告厅
Selected Publications:
1. Tengfei Zhang, Shiwen Wang, Yan Lin, Wei Xu, Dan Ye, Yue Xiong, * Shimin Zhao, * and Kunliang Guan*. (2012). Acetylation Negatively Regulates Glycogen Phosphorylase by Recruiting Protein Phosphatase 1. Cell Metabolism 15, 75–87.
2. Wenqing Jiang, Shiwen Wang, Mengtao Xiao,Yan Lin, Lisha Zhou,Qunying Lei,Yue Xiong,Kun-Liang Guan and Shimin Zhao*. (2011). Acetylation regulates gluconeogenesis by promoting PEPCK1 degradation via recruiting the UBR5 ubiquitin ligase. Molecular Cell 43, 33-44.
3. Yaohui Chen; Jinye Zhang; Yan Lin; Qunying Lei; Kun-Liang Guan; Shimin Zhao * and Yue Xiong*. (2011). Tumor suppressor SIRT3 deacetylates and activates manganese superoxide dismutase (SOD2) to scavenge ROS. EMBO Reports 12, 534-541.
4. Xu W, Yang H, Liu Y, Yang Y, Wang P, Kim S, Ito S, Yang C, Wang P, Xiao M, Liu L, Jiang W, Liu J, Zhang J, Wang B, Frye S, Zhang Y, Xu Y, Lei Q, Guan K*, Zhao S* and Y. Xiong*. (2011). Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α- ketoglutarate-dependent dioxygenases. Cancer Cell 19, 17-30.
联系人:纪建国(电话:62755470)
欢迎各位老师和同学积极参加!