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Identifying complex motifs in massive omics data with a variable-convolutional layer in deep neural network

DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes

Genomic evidence for the Chinese mountain cat as a wildcat conspecific (Felis silvestris bieti) and its introgression to domestic cats

Genome-wide interrogation of gene functions through base editor screens empowered by barcoded sgRNAs

3D Genome Alterations Associated with Dysregulated HOXA13 Expression in High-Risk T-Lineage Acute Lymphoblastic Leukemia

Fanconi anemia proteins participate in a break-induced-replication-like pathway to counter replication stres

The intra-S phase checkpoint directly regulates replication elongation to preserve the integrity of stalled replisomes

Transcription shapes DNA replication initiation to preserve genome integrity

Detect-seq reveals out-of-protospacer editing and target-strand editing by cytosine base editors

Chemically Defined and Xeno-free Culture Condition for Human Extended Pluripotent Stem Cells

Evolutionary driving forces of A-to-I editing in metazoans

Mouse totipotent stem cells captured and maintained through spliceosomal repression

Global miRNA dosage control of embryonic germ layer specification

A central circadian oscillator confers defense heterosis in hybrids without growth vigor costs

Golgi apparatus-synthesized sulfated glycosaminoglycans mediate polymerization and activation of the cGAMP sensor STING

Biological pathway expression complementation contributes to biomass heterosis in Arabidopsis

Probing bacterial cell wall growth by tracing wall-anchored protein complexes

The STING Phase-Separator Suppresses Innate Immune Signaling

A genetically encoded sensor for measuring serotonin dynamics

Transcriptional regulation of intermolecular Ca2+ signaling in hibernating ground squirrel cardiomyocytes: The myocardin–junctophilin axis