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Geometry of sequence working memory in macaque prefrontal cortex

Engineered circular ADAR-recruiting RNAs increase the efficiency and fidelity of RNA editing in vitro and in vivo

Integrated Genomic Analyses Identify High-Risk Factors and Actionable Targets in T-Cell Acute Lymphoblastic Leukemia

Human pluripotent stem-cell-derived islets ameliorate diabetes in non-human primates

RALF peptide signaling controls the polytubey block in Arabidopsis

The PCY-SAG14 phytocyanin module regulated by PIFs and miR408 promotes dark-induced leaf senescence in Arabidopsis

Overcoming resistance to immune checkpoint therapy in PTEN-null prostate cancer by intermittent anti-PI3Kα/β/δ treatment

Deubiquitinase OTUB2 exacerbates the progression of colorectal cancer by promoting PKM2 activity and glycolysis

Structural insights into the membrane microdomain organization by SPFH family proteins

Exogenous artificial DNA forms chromatin structure with active transcription in yeast

A sensitive GRAB sensor for detecting extracellular ATP in vitro and in vivo

NuMA regulates mitotic spindle assembly, structural dynamics and function via phase separation

Quantitative model suggests both intrinsic and contextual features contribute to the transcript coding ability determination in cells

Structure, function and pharmacology of human itch receptor complexes

A fluorescent sensor for spatiotemporally resolved imaging of endocannabinoid dynamics in vivo

Noncoding loci without epigenomic signals can be essential for maintaining global chromatin organization and cell viability

Sensing of cytoplasmic chromatin by cGAS activates innate immune response in SARS-CoV-2 infection

Increasing the efficiency and precision of prime editing with guide RNA pairs

RAG2 abolishes RAG1 aggregation to facilitate V(D)J recombination

T6SS translocates a micropeptide to suppress STING-mediated innate immunity by sequestering manganese